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Modafinil – The ‘Smart Drug’ Leading The Charge Towards A Future Of Neuroenhancement

Many students at Cambridge, Oxford and Harvard universities have already tested and approved. Now it is the turn of a study to point out that modafinil (also sold as Provigil) improves concentration, attention, and ability to learn, without leaving sequels as a chemical addiction. What Modafinil does is to act on the cognitive functions of the human brain. The drug acts directly on so-called “fluid intelligence,” which we use to solve problems and think in a more creative way.

As with Viagra, initially developed to treat blood circulation, modafinil was not born with the task of replacing strong coffee in the dawn of the students. The remedy should prevent people with narcolepsy from falling asleep and then adapted so that soldiers could stay awake at night. Gradually, it was noted that in addition to improving alertness, there were other “interesting” effects, such as increased concentration power. For students with a tendency to be easily distracted, it was seen as the solution for the exams season or for the completion of theses and master’s degrees.Modafinil has been used in this way for some time. A poll conducted in 2008 with readers of Nature indicated that nearly half admitted they had already used the drug to increase their cognitive ability.

Although sold under prescription in the United States and the United Kingdom, several students report that it is relatively easy to buy the medicine. You can purchase variations on online sites under the name Provigil, Modalert, and Modapro. The study, published in the European Neuropsychopharmacology, considered 24 research conducted between 1990 and 2014. The remedy was given to healthy patients, who had not spent hours without sleep.

What the new study does not reveal, however, is what the side effects are in the medium term. Previous studies with other substances touted as “smart drugs” have lost their effect in a short time. In very creative people, we observed a drop in yield, but nothing consistent that could pass from observation in the study.

Barbara Sahakian, a specialist in neuropsychology at the University of Cambridge, has been extensively researching the effects of modafinil. “Many students may feel pressured to take the medication before taking their final exams – even if they believe this is wrong. In competitive situations, such as getting a spot, I wonder if it would not be the case to ban this drug, just as it is in sports.

John Fabiano, who studied the caffeine effect for cognitive functions and is a researcher at Oxford University, said Modafinil should be looked at in the same way as caffeine. And that its effects go far beyond improving mood and creating the sensation of being alert without the risk of addiction.

It’s important to remember, however, that the study is not decisive. Other drugs came to be cited as a solution to problems – to later become “villains.” It took doctors to realize that Vicodin, prescribed for intense pain, was capable of vitiating the patient – as was the case with actress Jamie Lee Curtis, actor Matthew Perry, and rapper Eminem.


Considered the main “intelligence pill” of the moment, modafinil has been popularized by powerfully increasing the concentration of healthy individuals, as well as allowing the study or the accomplishment of tasks that require concentration for long periods (which may exceed 48 hours), without The need for sleep, and apparently (as far as studies already conducted indicate), without charging the debt for lack of sleep afterwards, as with caffeine and other stimulants. There may, however, be long-term effects that remain unknown.

Modafinil does not increase intelligence, only concentration, and therefore performance on tasks that require concentration (such as long hours of study or work). It may, however, decrease performance on other cognitive tasks. One of the alleged advantages of modafinil is that it would not cause significant chemical dependency.


Irritability, excitement, tremors, dizziness, headache, nausea, abdominal pain, high blood pressure, and palpitations. Its advantage over amphetamines is the fact that it does not provoke a change in the senses that could hinder decision-making or create physical dependence. In clinical trials, only about 1% of the volunteers complained about the side effects. ”


The lack of continuous sleep due to the use of Modafinil has not yet had side effects (which may, however, manifest in the long term).tis, pulvinar dapibus leo.


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